Good afternoon,
Friends and Family,
Today Dr. Andrew Co, from UCSF Cancer, called and confirmed:
Johnny has been randomized into "ARM A" for the clinical trial.
Good news this means he will receive the following: this is the main drug we wanted him to be on.
Cyclophosphamide/GVAX Pancreas vaccine and CRS-207 over the following weeks:
2 doses of Cyclophosphamide and GVAX Pancreas vaccine, three weeks apart;
4 doses of CRS-207, 3 weeks apart;
total of 80 patients includes our Johnny
this trial is a total of 20 weeks. Dr. Andrew Co. hopes this will help Johnny. Know that this is not a cure it's helping Johnny.
As a reminder:
GVAX Pancreas Vaccine, sponsored by Aduro Biotech. Only 240 people will be enrolled, from different participation centers. The GVAX pancreas vaccine is made from other patient’s pancreatic cancer cells. The cells were changed in a laboratory to make a protein called GM-CSF. This is done by putting the GM-CSF gene into the pancreatic cells. A gene is a piece of protein (DNA) with a message on it that tells a cell to make something. In this case the message is to make more GM-CSF than it would normally make. GM-CSF helps to activate the immune systems cells to recognize and attack the cancer cells. Because a gene was inserted into the cells of the other patient’s cancer cells to make this vaccine it is therefore called “gene therapy”.
Johnny has been having a miserable time, we both have of recent.
Please keep sending you love and emails: johnnypye@yahoo.com he does enjoy reading them.
Regards
Michelle & Johnny
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